The EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) has assessed the safety of the yeast biomass of Yarrowia lipolytica yeast biomass as a novel food pursuant to the Novel Food Regulation (EU) 2015/2283. In its assessment, the Panel concluded that the dried and heat-treated yeast biomass pose no health risks as a result of the its manufacturing process. Thus, no further toxicological data are needed and the yeast biomass of Yarrowia lipolytica is considered safe. You can have access to the full EFSA opinion here.
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