a&r’s News Digest – We dedicate this May issue to Vitafoods Europe and some general news. Also, we have decided to repeat our seminar on the regulatory challenges for CBD-based products in the EU. Join us in June!


Business opportunities and Education

We’re doing it again!

Due to the overwhelming interest and the very positive feedback from our participants, we are pleased to announce a new date for our regulatory seminar on the current regulatory situation for cannabidiol-containing food products in the EU.

The interactive seminar will provide an overview of the regulatory challenges that food business operators currently face and will explain the requirements for the submission of Novel Food applications for CBD in foods/supplements. Examples will be given under which conditions shared applications might be useful.

Date: 27th of June 2019
Time: 10am – 3pm
Location:  Regus Excellent Business Center, Europaplatz 2, 10557 Berlin – Germany

Participants will have the opportunity to discuss specific questions with our regulatory experts.

Limited number of participants!

If you want to know more about the seminar and/or still want to register, please click here.

a&r at Vitafoods Europe 2019

Vitafoods Europe is the perfect place to learn what is happening in the nutraceutical market. The show offers an excellent opportunity to engage in in-depth conversations with clients about opportunities in natural health products innovation. We hope you were able to find some time to stop by our booth and meet the team. We certainly had a great time meeting you. This year the show opened the doors to over 1,300 businesses and over 22,000 visitors.

During the event, our colleague Dr Heike Stier contributed to the most popular session on CBD regulations with a presentation on “Is it high-time for CBD supplements in EU?” We also had the chance to chair a session on “Nutricosmetics: Eating for Beauty” by our experts Dr. Inês Rocha and Dr. Iris Hardewig. We also contributed with a talk on “Innovation in probiotics”.

Nutricosmetics was definitely one of the buzzwords of this year’s show. The innovation tour on this topic was completely overcrowded with participants. Although not a new concept, nutricosmetics are on the rise. However, they are bringing a new and deeper concept to the market, which does not only focus on the appearance of skin, hair, or nails per se, but is a more holistic approach to healthy aging. Today, consumers are taking more preventative, holistic, and eco-conscious approaches to their health, personal care and lifestyles. Thus, with the line between wellness and beauty blurring, if you feel good inside then this will show on the outside. It is no longer beauty for beauty’s sake, but healthy beauty – the healthy glow.

Out of all the ingredients in this segment, collagen continues to show a strong presence. Brands are using collagen in various delivery formats to target beauty from within; they are adding it to waters and juices, and it was also found in individualized drinking sticks. New and innovative ingredients were also presented during the show in this segment such as DracoBell™ Nu from Mibelle Biochemisty, an ingredient from Moldavian Dragonhead (Dracocephalum moldavica).

Probiotics are here to stay, not only in the food supplement space but also in topical formulations, for instance targeting skin conditions such as atopic dermatitis (Symbio dermal by Symbio Pharma). With consumers gaining more and more awareness of probiotics and their potential health benefits, companies continue to invest more in clinical data to support their ingredients. New delivery systems also allow the combination of probiotics with other ingredients for specific health benefits, enabling the probiotics to be stable and inactive until they reach the intestine (e.g. Duocap™ combo for probiotics by Lonza-Capsugel).

Essential oils are also on the rise. We have seen them added to chewable softgels targeting sore throat and blocked nose (Respichew by Liv-Active), in combination with active ingredients in a smart capsule to be used in water bottles targeting detoxification, blood circulation and cellulite (from Robertet), as well as in antispasmodic preparations (Spasmoil from Solé Pharma).

The use of confectionary as well as snacks/functional beverages and healthy drinks played a big role this year. Brands continue to use healthy confectioneries such as fruit drops and gummies to drive innovation. Brands are also using bakery functional snacks (e.g. with a blend of botanical extracts to target cholesterol management, by EPO Srl) as well as drink formats (e.g. protein water by Friesland Campina with its whey protein isolate, or beauty collagen water by Weishardt with its fish collagen peptides) to deliver functional ingredients. Chewing gums were another big trend as an innovative delivery system. Chewing gums were available mixed with vitamins, e.g. K2vital, a gum containing vitamin K2 and vitamin D3 from Kappa Bioscience, or containing functional ingredients such as collagen, Aloe vera, or fibers (by Pissa, a confectionery manufacture solution based in Mexico).

Cannabis sativa extracts and/or its compounds continue to gain more and more attention from the market. The medicinal use of cannabis is now legal in Europe, but the regulatory situation around CBD and its use in food is still far from being harmonized. During the show, we were able to contribute to the discussions around the opportunities for CBD and hemp extracts.

Sustainability and traceability are also important keywords. Plant-based growth has been a key theme for several years, but the extent to which it would grow into the mainstream with both vegetarian and vegan options became clear during 2018. Consumers are demanding more transparency for products, searching for brands that they can trust and that have an environmentally friendly approach and consider animal welfare. Companies are thus increasing their portfolio of clean label supplement products, providing more vegetarian and vegan options for the delivery of food supplements with, for example, plant-based capsules addressing the growing demand for opaque capsules that do not include titanium dioxide (Vcaps Plus White Opal capsule by Lonza-Capsugel). Natural sources for vitamins and minerals continue to gain more and more importance. During the show, Naturex showcased Ultimine™, an organic source of iron produced using Koji fermentation technology. Also, discussions around the opportunities of blockchain for the food industry were discussed during the show.

Key health areas that caught our attention were eye/vision, recovery as well as energy boosters, sleep, liver, and brain health.

Personalized nutrition technologies also took center stage during the show. Experts in the field are pointing to the role of wearable devices, mobile apps, and forward-looking options such as genetic profiling.

As already noticeable in the last editions, the market of sport nutrition continues to rise with more and more consumers interested in healthy living and active lifestyles.

If you did not find the time to meet us but have questions regarding regulations, scientific marketing, strategic innovation, licensing and matchmaking, or clinical research, then get in touch today. We will be happy to support you!


Joint Fi Europe and Hi Europe

In case you have not yet noticed, Fi Europe, the leading trade show for food and beverage ingredients, and Hi Europe, its counterpart for health ingredients, will become co-located events alternating between Germany and France.
The first shared event by Fi Europe and Hi Europe will take place in Frankfurt (Germany) from 1st to 3rd December 2020. The trade show will cover food ingredients as well as processing solutions and services across the entire supply chain.

EFSA dedicated support for small and medium-sized enterprises (SMEs)

EFSA will extend their dedicated services to applicants from small and medium-sized enterprises (SMEs). SMEs will now be able to access support from EFSA when preparing, submitting, and monitoring their applications for regulated products.
EFSA will use the experience gained in providing these new forms of support to decide whether to include them in its catalogue of support initiatives.
Therefore, companies interested in these EFSA support initiatives can learn how to access them via the EFSA applications section.

NutraBusiness Intel

Bionorica sells cannabis business to Canopy Growth

May 2nd, 2019

Bionorica SE has sold its cannabis business to Canopy Growth Corporation, a world-leading, diversified cannabis and hemp company based in Canada. The selling price amounts to 225.9 million Euros. The existing locations in Neumarkt, Frankfurt and Vienna will be continued.
Bionorica will support Canopy Growth in the future, and both companies see great opportunities in the further clinical research of the cannabis plant and its ingredients.

PharmaNutra signs new international agreements for Cetilar®

May 6th, 2019

PharmaNutra S.p.A, an Italian based pharmaceutical company dedicated to the development of nutraceutical supplements and medical devices, has made new agreements for the distribution of their Cetilar® products in Turkey, Romania and Taiwan. Cetilar® is a medical device for reducing painful post-trauma symptoms in muscles and joints containing olive oil (European olea), apricot oil (Prunus armeniaca), beeswax, wheat germ oil (Triticum vulgare), and vitamin E.

Nestlé in exclusive negotiations on Skin Health

May 16th, 2019

Nestlé announced that it has entered into exclusive negotiations with a consortium led by EQT and a wholly owned subsidiary of the Abu Dhabi Investment Authority (ADIA) for the sale of Nestlé Skin Health for a value of CHF 10.2 billion (USD10.1 billion).
Nestlé Skin Health range offers medical and consumer brands through three complementary business units in prescription, aesthetics, and consumer care.

Novelties in our MatchMaking Platform

Now is the right time to start looking for a new product for cough & cold for your product portfolio. And we just added a new exciting licensing opportunity to our MatchMaking Platform! ID#94 is a well-established use herbal product for productive cough that is available in an innovative and convenient dosage form, an orodispersible thin film.

To learn more about this business opportunity, contact our MatchMaking expert at matchmaking@a-r.com.


‘Beauty from within‘ products are in great demand right now. Look no further – ask us about ID#74, a clinically supported food supplement in tablet form for maintenance of normal hair and skin condition.

To learn more about this business opportunity, contact our MatchMaking expert at matchmaking@a-r.com.


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Your experts

Irene Wohlfahrt
Irene WohlfahrtSenior Consultant
Dr. Inês Rocha
Dr. Inês RochaScientific Consultant

At analyze & realize, we are experts in the field of natural health products, having provided our services for more than 20 years. We offer a unique combination of expertise in natural health products through our scientific, regulatory, and strategic innovation consulting and our clinical research organization with its own clinical trial center in Berlin, Germany. Thanks to our close interaction with the natural product market as well as our extensive network, we are always at the forefront of the latest information and innovation trends. With its international team of 35 employees, a&r is a leading European one-stop-shop ready to guide and support your needs in natural health product innovation.

Don’t hesitate to contact us: newsletter@a-r.com